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Pain in the Palm of the Hand: Causes, Symptoms & Treatment

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Dr. Karn Maheshwari

Medically reviewed by Dr. Karn Maheshwari, MS Ortho, DNB, FNB Hand Surgery · Krisha Hand Hospital, Ahmedabad · 

Pain in the Palm of the Hand

Pain in the palm of the hand can range from a temporary problem caused by overuse to a condition involving the tendons, nerves, joints, bones, blood vessels, or other soft tissues.

You may notice pain in the palm of your hand when pressing, a sudden sharp pain, throbbing or burning discomfort, tenderness near the base of a finger, or pain while gripping objects. The location, duration, and associated symptoms can provide useful clues about the underlying cause.

But when is palm pain something you can monitor at home, and when should you see a hand specialist?

This guide explains the common causes of palm pain, different types of symptoms, warning signs, treatment options, and when medical evaluation may be appropriate.

There are many possible causes of pain in the palm of the hand, including:

  • Overuse or repetitive hand movements
  • Muscle or soft-tissue strain
  • Tendon inflammation or injury
  • Trigger finger and A1 pulley problems
  • Carpal tunnel syndrome and other nerve compression conditions
  • Nerve injuries
  • Arthritis
  • Hand or finger injuries
  • Fractures
  • Ligament injuries
  • Dupuytren’s disease
  • Ganglion cysts or other localized masses
  • Foreign bodies such as splinters
  • Infections
  • Vascular or circulation-related problems
  • Less common conditions affecting nerves, blood vessels, bones, or soft tissues

Mild palm pain that clearly follows heavy or repetitive use may improve with activity modification. However, severe, persistent, recurrent, or unexplained palm pain deserves appropriate medical assessment, particularly when it affects sensation, strength, movement, or circulation.

What Does Palm Pain Feel Like?

Palm pain does not feel the same for everyone. Depending on its cause, you may experience:

  • Dull or aching pain
  • Sudden sharp pain in the palm
  • Throbbing pain
  • Burning or tingling
  • Pain when pressing the palm
  • Tenderness in one specific area
  • Pain while gripping objects
  • Pain when bending the fingers
  • Stiffness
  • Pain spreading toward the fingers or wrist
  • Numbness or altered sensation
  • Weakness or difficulty gripping

The type, exact location, duration, and accompanying symptoms can help a doctor narrow down the possible cause.

Common Causes of Pain in the Palm of the Hand

1. Overuse or Repetitive Hand Movements

Sometimes palm pain develops simply because the hand is being used repeatedly.

Typing, lifting, gaming, prolonged mobile-phone use, manual work, sports, or repetitive gripping can place stress on the muscles, tendons, and soft tissues of the hand.

You may experience:

  • Aching or soreness
  • Mild tenderness
  • Pain after prolonged activity
  • Stiffness
  • Temporary discomfort while gripping

If the pain is mild and clearly connected to a particular activity, reducing that activity and allowing the hand to recover may help.

However, pain that repeatedly returns despite activity modification may have another underlying cause.

2. Tendon Problems and Trigger Finger

Tendons connect muscles to bones and allow the fingers to move. Irritation or injury involving the flexor tendons or surrounding structures can cause pain in the palm, particularly around the base of a finger.

Trigger finger, for example, is associated with problems around the A1 pulley, where a finger tendon passes through a tight pulley system.

Symptoms may include:

  • Pain or tenderness at the base of a finger
  • Finger stiffness
  • Clicking or catching
  • Difficulty moving the finger smoothly
  • A finger temporarily getting stuck while bending or straightening

Depending on severity, treatment may include activity modification, splinting, medication, injection, or surgery.

3. Carpal Tunnel Syndrome and Nerve Compression

Nerve-related pain can feel different from muscle or tendon pain.

Carpal tunnel syndrome (CTS) occurs when the median nerve is compressed at the wrist. Symptoms commonly involve the thumb, index finger, middle finger, and part of the ring finger and may include:

  • Numbness
  • Tingling
  • Burning sensations
  • Hand or finger discomfort
  • Symptoms that are worse at night
  • Weakness or difficulty gripping in more advanced cases

Not every type of palm pain is caused by carpal tunnel syndrome. The distribution of numbness or tingling and the findings on examination help determine whether the median nerve is involved.

Other nerve compression or nerve-related conditions can produce different patterns of symptoms.

4. Hand or Finger Injury

A fall, sports injury, workplace accident and crush injury, or direct blow can damage the:

  • Bones
  • Tendons
  • Ligaments
  • Nerves
  • Blood vessels
  • Soft tissues

Importantly, a small skin wound does not always mean a minor hand injury. Tendon, nerve, or ligament damage can sometimes exist beneath a relatively small wound.

Similarly, a normal X-ray does not rule out every type of soft-tissue injury.

Possible symptoms include:

  • Sudden pain after trauma
  • Swelling
  • Bruising
  • Reduced finger movement
  • Difficulty gripping
  • Localized tenderness
  • Numbness
  • Deformity

Significant hand trauma should be assessed appropriately, especially when normal hand function has changed.

5. Arthritis

Arthritis can affect the joints of the hand and fingers and may cause:

  • Pain
  • Stiffness
  • Swelling
  • Reduced movement
  • Discomfort while gripping

Symptoms may become more noticeable after periods of inactivity, during movement, or with repeated use of an affected joint.

The specific symptoms depend on the type of arthritis and which joints are involved.

6. Dupuytren’s Disease

Dupuytren’s disease affects the connective tissue beneath the skin of the palm.

It can cause thickened tissue or nodules in the palm and, over time, may lead to tightening of the fingers.

Possible signs include:

  • A firm lump or nodule in the palm
  • Tight or thickened tissue
  • Difficulty placing the hand flat
  • Progressive limitation in finger movement

Not every palm lump is Dupuytren’s disease, so a clinical examination is important when a new or persistent lump develops.

7. Ganglion Cyst or Other Mass

A ganglion cyst is a fluid-filled lump that commonly develops around joints or tendons. Although ganglion cysts are more frequently noticed around the wrist, other localized masses can also occur in or around the hand.

A mass may cause:

  • Localized tenderness
  • Pressure-related discomfort
  • Pain during movement or gripping
  • A visible or palpable lump

Persistent or unexplained lumps should be evaluated rather than assumed to be a ganglion cyst.

8. Foreign Body

A splinter, piece of glass, metal fragment, or another foreign body can sometimes become embedded in the hand.

This may cause:

  • Very localized tenderness
  • Pain when pressing the area
  • Swelling
  • Redness
  • Persistent discomfort
  • Infection if the foreign material remains in place

If palm pain began after a penetrating injury and remains localized to one spot, a foreign body may need to be considered.

9. Infection

Hand infections can cause rapidly increasing pain and swelling.

Possible warning signs include:

  • Increasing redness
  • Warmth
  • Swelling
  • Severe tenderness
  • Pus or discharge
  • Fever
  • Increasing pain
  • Difficulty moving a finger

Some infections can involve deeper hand structures and may require prompt medical treatment, including antibiotics and, when necessary, surgical drainage.

10. Vascular and Less Common Nerve Conditions

Less commonly, palm or finger pain may be related to blood vessels, circulation, or unusual nerve conditions.

Circulation-related symptoms may be particularly concerning when pain occurs with a pale, blue, unusually cold, or otherwise abnormal-looking finger.

Some nerve conditions can also produce burning, shooting, electric-like pain, altered sensation, or localized sensitivity.

Because these conditions can overlap with more common problems, persistent or unusual symptoms should be assessed clinically.

Where Exactly Does Your Palm Hurt?

The location of palm pain can provide additional clues, although location alone cannot establish a diagnosis.

Pain at the base of the thumb

Possible causes include tendon problems, joint conditions, ligament problems, or irritation of structures supporting the thumb.

Pain near the base of the fingers

This may occur with conditions such as trigger finger, A1 pulley problems, tendon irritation, or finger-joint conditions.

Pain in the centre of the palm

Possible causes include soft-tissue strain, tendon problems, nerve-related conditions, Dupuytren’s disease, or other localized conditions.

Pain near the little finger or Pinky side

Pain on the ulnar side of the hand can have different causes involving the palm, wrist, tendon, bone, ligament, or nerve.

A proper examination helps determine which structure is actually responsible.

Pain in Palm of Hand When Pressure Is Applied

If your palm hurts when pressure is applied, the cause may depend on the exact location and whether other symptoms are present.

Possible causes include:

  • Local soft-tissue irritation
  • Minor injury or bruising
  • Tendon-related problems
  • Foreign body or splinter
  • Localized nerve irritation
  • Joint or bone problems
  • Infection
  • Dupuytren’s nodule
  • Ganglion or another localized mass

If one specific spot is extremely painful to touch, particularly when the tenderness is persistent or associated with unusual symptoms such as cold sensitivity, a medical evaluation may be appropriate.

Sudden Sharp Pain in the Palm: Is It Serious?

Sudden sharp pain in the palm does not automatically mean that something serious is wrong.

It can occur after a sudden movement, minor injury, irritated tissue, or nerve irritation.

However, sudden palm pain deserves prompt assessment when it occurs with:

  • Significant injury
  • Severe swelling
  • Visible deformity
  • Loss of sensation
  • Sudden weakness
  • Inability to move a finger or hand normally
  • Pale, blue, or unusually cold fingers
  • Severe or rapidly worsening pain
  • Signs of infection

These symptoms may indicate an injury or condition requiring timely medical attention.

Throbbing or Burning Pain in the Palm

The character of pain can sometimes provide clues, but it cannot establish a diagnosis by itself.

Throbbing pain may occur with inflammation, injury, or infection.

Burning, shooting, or electric-like pain may be more suggestive of nerve irritation.

Pain accompanied by numbness or tingling can indicate nerve involvement.

Because different conditions can produce similar symptoms, the overall pattern and clinical examination are important.

When Palm Pain Needs Prompt Medical Attention

Seek prompt medical attention if palm pain is associated with:

  • Loss of sensation
  • Inability to move a finger or hand normally
  • Significant deformity
  • Rapidly increasing swelling
  • Severe or rapidly worsening pain
  • Pale, blue, or unusually cold fingers
  • Major weakness
  • Significant injury or crush trauma
  • Pus, fever, spreading redness, or other signs of infection

These symptoms should not be managed solely with home treatment.

When Should You See a Doctor for Palm Pain?

Consider medical evaluation if:

  • The pain persists or repeatedly returns
  • The pain is getting progressively worse
  • You have numbness or tingling
  • Your grip is becoming weaker
  • Finger movement is restricted
  • There is persistent swelling
  • Pain started after a significant injury
  • You notice a lump or unusual swelling
  • There is redness, warmth, pus, or fever
  • The pain interferes with work or everyday activities

The sooner the underlying cause is identified, the easier it may be to determine an appropriate treatment plan.

How Is the Cause of Palm Pain Diagnosed?

A doctor may begin with a detailed examination of your:

  • Palm
  • Fingers
  • Wrist
  • Tendons
  • Nerves
  • Joints
  • Hand strength
  • Finger and wrist movement
  • Sensation and circulation

Depending on the suspected cause, investigations may include:

  • X-ray
  • Ultrasound
  • MRI
  • Nerve conduction studies/EMG
  • Blood tests in selected cases

Not everyone with palm pain needs every test. The appropriate investigation depends on the symptoms and clinical examination.

Treatment for Pain in the Palm of the Hand

Treatment depends on the underlying cause, rather than the pain alone.

Cause

Possible Treatment

Overuse

Activity modification, rehabilitation, gradual return to activity

Trigger finger / A1 pulley problem

Splinting, injection, or surgery depending on severity

Carpal tunnel syndrome

Night splinting, activity modification, injections, or surgical release when indicated

Fracture

Immobilization, reduction, or fixation depending on the injury

Tendon injury

Repair when required followed by structured rehabilitation

Nerve injury

Nerve repair/reconstruction and rehabilitation when indicated

Arthritis

Activity modification, medication, therapy, injections, or surgery depending on the condition

Infection

Prompt medical treatment, antibiotics and drainage when required

Foreign body

Removal when necessary, with treatment of associated tissue damage or infection

Mass or cyst

Observation, investigation, or treatment depending on the diagnosis

The appropriate treatment should be determined after identifying the specific condition.

Can You Treat Palm Pain at Home?

If the pain is mild, recent, and clearly related to temporary overuse or a minor strain, initial supportive measures may sometimes include:

  • Resting the affected hand
  • Temporarily avoiding activities that aggravate the pain
  • Using cold therapy appropriately for a recent minor injury
  • Gentle movement within a comfortable range
  • Gradually returning to normal activities as symptoms improve

However, home treatment should not replace medical assessment when the diagnosis is uncertain or symptoms are severe, persistent, worsening, or associated with numbness, weakness, significant swelling, deformity, circulation changes, or infection.

When Is a Hand Specialist Appropriate?

Most people with occasional mild hand discomfort do not necessarily need to see a hand surgeon immediately.

A hand specialist becomes particularly relevant when symptoms are:

  • Persistent or recurrent
  • Function-limiting
  • Associated with significant trauma
  • Affecting nerves or sensation
  • Affecting tendon function
  • Associated with fractures or ligament injuries
  • Related to difficult or recurrent tendon conditions
  • Suggestive of complex hand injury
  • Potentially requiring reconstruction or microsurgical treatment

The goal is not simply to treat the pain; it is to identify and treat the underlying cause whenever possible.

Why See a Dedicated Hand & Microsurgery Specialist?

The hand contains bones, joints, tendons, nerves, blood vessels, ligaments, and soft tissues within a relatively small anatomical area.

Problems involving these structures can sometimes look similar from the outside but require very different treatment approaches. This is particularly important after significant trauma, when sensation or movement is affected, or when a condition involves delicate nerves, tendons, blood vessels, or other complex structures.

A hand and microsurgery specialist can evaluate the affected structures and determine whether further investigation, conservative treatment, rehabilitation, surgery, or microsurgical reconstruction may be appropriate.

If persistent or function-limiting palm pain is affecting your daily activities, consult a qualified hand and wrist specialist for an appropriate evaluation.

References

For additional patient education, readers may refer to the following organizations:

American Society for Surgery of the Hand (ASSH)

American Academy of Orthopaedic Surgeons (AAOS)

National Health Service (NHS)

Frequently Asked Questions

Not necessarily. Mild palm pain can result from overuse or a minor strain. However, persistent, severe, worsening, or unexplained pain especially with numbness, weakness, swelling, or reduced movement should be medically evaluated.

Localized tenderness can occur because of minor injury, soft-tissue irritation, tendon problems, a foreign body, infection, nerve irritation, a localized mass, or other conditions. Persistent or severe localized tenderness should be assessed.

Sudden sharp pain can occur after a sudden movement, injury, irritated tissue, or nerve irritation. If the pain is severe or accompanied by numbness, weakness, swelling, deformity, circulation changes, or loss of normal hand function, seek prompt medical attention.

Carpal tunnel syndrome can cause discomfort, burning, tingling, or numbness in the hand, particularly involving the thumb, index, middle, and part of the ring finger. However, not every type of palm pain is caused by CTS.

Yes. Trigger finger commonly causes tenderness or pain around the base of the affected finger in the palm, along with stiffness, clicking, catching, or difficulty moving the finger smoothly.

Yes. A small skin wound can sometimes be associated with deeper tendon, nerve, ligament, or vascular injury. Changes in finger movement or sensation after an injury should be evaluated.

Consider specialist evaluation when palm pain is persistent, recurrent, significantly affects hand function, follows significant trauma, or is associated with suspected tendon, nerve, bone, ligament, or other complex hand problems.

Some mild overuse-related pain may improve with rest and activity modification. Persistent or recurrent symptoms, however, may indicate an underlying condition that requires evaluation.

Dr. Karn Maheshwari

FNB (Hand & Microsurgery) | MS Ortho | DNB Ortho | Founder, Krisha Hand Hospital

Dr. Karn Maheshwari is the founder of Krisha Hand Hospital, Ahmedabad, established in 2016. He is the only FNB-qualified hand surgeon across Gujarat, Rajasthan, and Madhya Pradesh.

With MS and DNB in Orthopedics, Dr. Maheshwari specializes in treating a wide range of hand and wrist conditions, including carpal tunnel syndrome, sports hand injuries, orthopedic hand surgery, ganglion cysts, mangled hand injuries, congenital hand differences, brachial plexus palsy, cerebral palsy & spastic hand, hand tendinopathy, hand microsurgery, hand swelling, hand transplants, hand reimplantation, rheumatoid hand deformities, and peripheral nerve injuries & compressive neuropathies.

Dr. Maheshwari’s unmatched expertise and patient-centric approach ensure world-class treatment, advanced surgical solutions, and optimal recovery for patients with complex hand and wrist conditions.

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